Human urocortin (hUcn) II is a new member of the corticotropin-releasing-factor (CRF) family. It selectively binds to the CRF2 receptor. Human urocortin II exhibits mild motor-suppressive effects and delayed anxiolytic-like effects，suggesting a time-dependent role for hUcn II in the regulation of stress-related behavior.

Ethyl 6-hydroxyhexanoate can be used to synthesize 2-Bu suberic acid.

Substance P 1-7 is the major bioactive metabolite formed after proteolytic degradation of the tachykinin substance P (SP)with anti-inflammatory anti-nociceptive and anti-hyperalgesic effects.